Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity relevant to bortezomib, a proteasome inhibitor Utilized in the remedy of many myeloma. Its synthesis or review is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor from the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-1): A critical compound from the synthesis of imatinib, a drug that targets particular kinds of cancer, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for instance breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their examine is important for optimizing the output system and making certain high purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to treat breast cancer, and these intermediates are involved in its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an Irinotecan hydrochloride trihydrate estrogen receptor antagonist Employed in the treatment of breast most cancers. Several intermediates help in the synthesis of the 5R)-3-Benzoyl-2-(4-methoxyphenyl)-4-phenyl-5-oxazolidinecarboxylic acid drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug productive in dealing with cancers for example ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the therapy of colorectal cancer and tiny mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is associated with the synthesis of adamantane derivatives, that have various programs, together with antiviral Homes.
Vildagliptin Intermediates: Utilized in the production of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-4 to regulate blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is linked to the synthesis of assorted gluconic acid derivatives, which happen to be used in meals, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor during the synthesis of canagliflozin, a medication utilized to manage variety two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).